3D-MPLA-3A

Full Name: 3-O-deacylated-4'-monophosphoryl lipid A (3-DMPLA) Form: 3-acylated form, characterized by a tri-acyl carbon chain structure. Source: Derived from the Lipopolysaccharide (LPS) of Salmonella minnesota Re595.

Specifically designed for immunological research, particularly in exploring the Structure-Activity Relationship (SAR) of the TLR4 receptor.Compared to the potent 6-acyl (6A) version, the 3A variant exhibits minimal activity in human immune cells and possesses potential antagonistic properties. It serves as a promising candidate for therapeutic drug development in autoimmune and allergic diseases.